CK2B Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit. Belongs to the casein kinase 2 subunit beta family. Note: This description may include information from UniProtKB.
Protein type: Protein kinase, regulatory subunit
Chromosomal Location of rat Ortholog: 20p12
Cellular Component:  cell projection; chromatin; cytoplasm; nuclear matrix; nucleus; PcG protein complex; plasma membrane; PML body; protein kinase CK2 complex
Molecular Function:  chromatin binding; identical protein binding; metal ion binding; protein domain specific binding; protein kinase regulator activity; protein serine/threonine kinase activity; protein-macromolecule adaptor activity; ribonucleoprotein complex binding; RNA polymerase II-specific DNA-binding transcription factor binding; signaling receptor binding
Biological Process:  adiponectin-activated signaling pathway; endothelial tube morphogenesis; liver regeneration; negative regulation of blood vessel endothelial cell migration; negative regulation of viral life cycle; peptidyl-threonine phosphorylation; phosphorylation; positive regulation of activin receptor signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; protein phosphorylation; response to testosterone; Wnt signaling pathway
Reference #:  P67874 (UniProtKB)
Alt. Names/Synonyms: casein kinase 2, beta subunit; casein kinase II beta subunit; Casein kinase II subunit beta; CK II beta; Ck2; CK2B; Ck2n; CSK2B; Csnk2b; Phosvitin
Gene Symbols: Csnk2b
Molecular weight: 24,942 Da
Basal Isoelectric point: 5.33  Predict pI for various phosphorylation states
CST Pathways:  Adherens Junction Dynamics  |  NF-kB Signaling
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Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene