APC13 Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Belongs to the APC13 family. Note: This description may include information from UniProtKB.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 3q22.2
Cellular Component:  anaphase-promoting complex
Molecular Function:  protein binding
Biological Process:  cell cycle; cell division; protein K11-linked ubiquitination
Reference #:  Q9BS18 (UniProtKB)
Alt. Names/Synonyms: ANAPC13; anaphase promoting complex subunit 13; Anaphase-promoting complex subunit 13; APC13; cyclosome subunit 13; Cylosome subunit 13; DKFZp566D193; homolog of yeast Swm1; SWM1
Gene Symbols: ANAPC13
Molecular weight: 8,521 Da
Basal Isoelectric point: 4.04  Predict pI for various phosphorylation states
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APC13

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein