KIF19 Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Microtubule-binding; Motor
Chromosomal Location of Human Ortholog: 11|11 E2
Cellular Component:  cell projection; cilium; cytoplasm; cytoskeleton; kinesin complex; microtubule
Molecular Function:  ATP binding; ATP-dependent microtubule motor activity, plus-end-directed; ATPase activity; microtubule binding; microtubule motor activity; nucleotide binding
Biological Process:  axonemal microtubule depolymerization; microtubule-based movement; plus-end specific microtubule depolymerization
Reference #:  Q99PT9 (UniProtKB)
Alt. Names/Synonyms: Kif19; Kif19a; KIF19A-like protein; kinesin family member 19A; Kinesin-like protein KIF19; N-8 kinesin; oocyte-G1; OTTMUSP00000031662
Gene Symbols: Kif19
Molecular weight: 111,559 Da
Basal Isoelectric point: 9.08  Predict pI for various phosphorylation states
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KIF19

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene