LAPTM4B Belongs to the LAPTM4/LAPTM5 transporter family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 15|15 B3.1
Cellular Component:  cell projection; early endosome; endosome; integral component of membrane; late endosome membrane; lysosomal membrane; lysosome; membrane; multivesicular body membrane; multivesicular body, internal vesicle; plasma membrane
Molecular Function:  ceramide binding; kinase binding; phosphatidylinositol bisphosphate binding; ubiquitin protein ligase binding
Biological Process:  endosome organization; endosome transport via multivesicular body sorting pathway; negative regulation of lysosomal protein catabolic process; negative regulation of transforming growth factor beta1 production; regulation of lysosomal membrane permeability; regulation of lysosome organization
Reference #:  Q91XQ6 (UniProtKB)
Alt. Names/Synonyms: C330023P13Rik; LAP4B; Laptm4b; LAPTM4beta; lysosomal-associated protein transmembrane 4B; lysosomal-associated transmembrane protein 4; Lysosomal-associated transmembrane protein 4B
Gene Symbols: Laptm4b
Molecular weight: 25,395 Da
Basal Isoelectric point: 5.16  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene