CDC40 Required for pre-mRNA splicing as component of the activated spliceosome. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis; RNA processing; RNA splicing; Spliceosome
Chromosomal Location of human Ortholog: 6q21
Cellular Component:  catalytic step 2 spliceosome; nuclear speck; nucleoplasm; U2-type catalytic step 2 spliceosome
Molecular Function:  mRNA binding; protein binding
Biological Process:  embryonic brain development; mRNA splicing, via spliceosome
Disease: Pontocerebellar Hypoplasia, Type 15
Reference #:  O60508 (UniProtKB)
Alt. Names/Synonyms: CDC40; cell division cycle 40; Cell division cycle 40 homolog; cell division cycle 40 homolog (S. cerevisiae); EH-binding protein 3; EHB3; FLJ10564; hPRP17; MGC102802; pre-mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRPF17
Gene Symbols: CDC40
Molecular weight: 65,521 Da
Basal Isoelectric point: 6.62  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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CDC40

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein