A-albumin Functions as carrier for hydrophobic molecules in body fluids. Essential for the solubility and activity of lipidated Wnt family members, including WNT1, WNT2B, WNT3, WNT3A, WNT5A, WNT7A, WNT7B, WNT8, WNT9A, WNT9B, WNT10A and WNT10B. Binds vitamin E. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the transport of vitamin E across the blood-brain barrier. Belongs to the ALB/AFP/VDB family. High level detected in plasma but also in extravascular fluids such as follicular and cerebrospinal fluids (at protein level). Note: This description may include information from UniProtKB.
Protein type: Carrier; Secreted; Secreted, signal peptide
Chromosomal Location of mouse Ortholog: 5|5 E1
Cellular Component:  extracellular region; extracellular space
Molecular Function:  vitamin E binding
Biological Process:  protein stabilization; protein transport; protein transport within extracellular region; vitamin transport
Reference #:  O89020 (UniProtKB)
Alt. Names/Synonyms: A-albumin; AFAM; Afamin; Afm; Alf; alpha albumin; Alpha-Alb; Alpha-albumin; MGC118711
Gene Symbols: Afm
Molecular weight: 69,379 Da
Basal Isoelectric point: 5.54  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene