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RASD2
GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination. Belongs to the small GTPase superfamily. RasD family. Pancreatic endocrine cells (islets of Langerhans). Note: This description may include information from UniProtKB.
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| Protein type: G protein; G protein, monomeric; G protein, monomeric, RasD |
| Chromosomal Location of human Ortholog: 22q12.3 |
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Cellular Component:
plasma membrane; synapse
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Molecular Function:
G-protein beta-subunit binding; GTP binding; GTPase activity
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Biological Process:
locomotory behavior; positive regulation of protein kinase B signaling; positive regulation of protein sumoylation; regulation of cAMP-mediated signaling; signal transduction; synaptic transmission, dopaminergic
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Reference #:
Q96D21
(UniProtKB)
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Alt. Names/Synonyms: GTP-binding protein Rhes; MGC:4834; Ras homolog enriched in striatum; RASD family member 2; RASD family, member 2; RASD2; Rhes; TEM2; Tumor endothelial marker 2
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Gene Symbols: RASD2
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Molecular weight:
30,366 Da
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Basal Isoelectric point:
9.09
Predict pI for various phosphorylation states
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