myomesin 1 iso2 Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17|17 E1.3
Cellular Component:  cytoplasm; cytoskeleton; M band; myosin filament; sarcomere; striated muscle thin filament; Z disc
Molecular Function:  actin filament binding; identical protein binding; kinase binding; muscle alpha-actinin binding; protein homodimerization activity; structural constituent of cytoskeleton; structural constituent of muscle
Biological Process:  cardiac muscle fiber development; cardiac muscle tissue morphogenesis; cardiac myofibril assembly; muscle contraction; positive regulation of gene expression; positive regulation of protein secretion; protein kinase A signaling; sarcomere organization; skeletal muscle myosin thick filament assembly; skeletal muscle thin filament assembly; striated muscle myosin thick filament assembly
Reference #:  Q62234-2 (UniProtKB)
Alt. Names/Synonyms: D430047A17Rik; MYOM1; myomesin 1; myomesin 1 iso2; Myomesin family member 1; Myomesin-1; skel; skelemin
Gene Symbols: Myom1
Molecular weight: 175,451 Da
Basal Isoelectric point: 5.95  Predict pI for various phosphorylation states
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myomesin 1 iso2

Protein Structure Not Found.


Cross-references to other databases:  Pfam  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene