GIMAP4 During thymocyte development, may play a role in the regulation of apoptosis. GTPase which exhibits a higher affinity for GDP than for GTP. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine. Note: This description may include information from UniProtKB.
Protein type: Hydrolase
Chromosomal Location of human Ortholog: 7q36.1
Cellular Component:  cytosol
Reference #:  Q9NUV9 (UniProtKB)
Alt. Names/Synonyms: FLJ11110; GIMA4; GIMAP4; GTPase IMAP family member 4; GTPase, IMAP family member 4; hIAN1; HIMAP4; human immune associated nucleotide 1; IAN-1; IAN1; IMAP4; immune-associated nucleotide-binding protein 1; immunity associated protein 4; Immunity-associated nucleotide 1 protein; Immunity-associated protein 4; MSTP062
Gene Symbols: GIMAP4
Molecular weight: 37,534 Da
Basal Isoelectric point: 7.66  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene