FETUA Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Belongs to the fetuin family. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Cellular Component:  extracellular membrane-bounded organelle; extracellular space; Golgi apparatus; plasma membrane; vesicle
Molecular Function:  cysteine-type endopeptidase inhibitor activity; protein binding
Biological Process:  acute-phase response; negative regulation of bone mineralization; ossification; positive regulation of phagocytosis; regulation of inflammatory response
Reference #:  P12763 (UniProtKB)
Alt. Names/Synonyms: AHSG; Alpha-2-HS-glycoprotein; Alpha-2-HS-glycoprotein precursor; Asialofetuin; FETUA; Fetuin-A
Gene Symbols: AHSG
Molecular weight: 38,419 Da
Basal Isoelectric point: 5.26  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein