MARCKS MARCKS is the most prominent cellular substrate for protein kinase C. This protein binds calmodulin, actin, and synapsin. MARCKS is a filamentous (F) actin cross-linking protein. Belongs to the MARCKS family. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 10 B1|10 19.49 cM
Cellular Component:  actin filament bundle; cell cortex; centrosome; cytoplasm; cytoskeleton; germinal vesicle; membrane
Molecular Function:  actin binding; actin filament binding; calmodulin binding; identical protein binding; protein kinase C binding
Biological Process:  actin crosslink formation; actin filament bundle assembly; protein homooligomerization
Reference #:  P26645 (UniProtKB)
Alt. Names/Synonyms: 80K protein; Macs; MARCKS; MARCS; myristoylated alanine rich protein kinase C substrate; Myristoylated alanine-rich C-kinase substrate; PKCSL
Gene Symbols: Marcks
Molecular weight: 29,661 Da
Basal Isoelectric point: 4.34  Predict pI for various phosphorylation states
CST Pathways:  Protein Kinase C Signaling
Select Structure to View Below

MARCKS

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene