PTDSS2 Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine. Belongs to the phosphatidyl serine synthase family. Note: This description may include information from UniProtKB.
Protein type: EC; Lipid Metabolism - glycerophospholipid; Membrane protein, integral; Membrane protein, multi-pass; Transferase
Chromosomal Location of Human Ortholog: 7|7 F5
Cellular Component:  endoplasmic reticulum; endoplasmic reticulum membrane; integral component of membrane; intracellular; membrane
Molecular Function:  CDP-diacylglycerol-serine O-phosphatidyltransferase activity; transferase activity
Biological Process:  lipid metabolic process; phosphatidylserine biosynthetic process; phospholipid biosynthetic process
Reference #:  Q9Z1X2 (UniProtKB)
Alt. Names/Synonyms: AI481134; AI988017; Phosphatidylserine synthase 2; PSS-2; Pss2; PtdSer synthase 2; Ptdss2; PTSS2; Serine-exchange enzyme II
Gene Symbols: Ptdss2
Molecular weight: 55,021 Da
Basal Isoelectric point: 6.64  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene