L-Myc a proto-oncogenic transcription factor. Targets include CCL6 chemokine gene. Plays a role in cell proliferation, apoptosis and in the development of human tumors. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 1p34.2
Cellular Component:  nucleus
Molecular Function:  DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; protein dimerization activity
Biological Process:  regulation of inner ear auditory receptor cell differentiation; regulation of transcription by RNA polymerase II
Reference #:  P12524 (UniProtKB)
Alt. Names/Synonyms: BHLHE38; Class E basic helix-loop-helix protein 38; L-Myc; l-myc protein; l-myc-1 proto-oncogene; LMYC; myc-related gene from lung cancer; MYCL; MYCL proto-oncogene, bHLH transcription factor; MYCL1; oncogene lmyc; Protein L-Myc; Protein L-Myc-1; v-myc avian myelocytomatosis viral oncogene homolog 1, lung carcinoma derived; v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog; V-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)
Gene Symbols: MYCL
Molecular weight: 40,327 Da
Basal Isoelectric point: 5.47  Predict pI for various phosphorylation states
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L-Myc

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein