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Kv11.3
Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.3/KCNH7 sub-subfamily. Expressed in prolactin-secreting adenomas. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass |
| Chromosomal Location of human Ortholog: 2q24.2 |
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Cellular Component:
plasma membrane
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Biological Process:
regulation of ion transmembrane transport
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Reference #:
Q9NS40
(UniProtKB)
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Alt. Names/Synonyms: eag related protein 3; Eag-related protein 3; ERG-3; ERG3; ether-a-go-go related gene potassium channel 3; Ether-a-go-go-related gene potassium channel 3; Ether-a-go-go-related protein 3; hERG-3; HERG3; KCNH7; Kv11.3; MGC45986; potassium channel subunit HERG-3; potassium channel, voltage gated eag related subfamily H, member 7; Potassium voltage-gated channel subfamily H member 7; potassium voltage-gated channel, subfamily H (eag-related), member 7; Voltage-gated potassium channel subunit Kv11.3
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Gene Symbols: KCNH7
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Molecular weight:
135,000 Da
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Basal Isoelectric point:
7.57
Predict pI for various phosphorylation states
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