Kv11.3 Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly. Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.3/KCNH7 sub-subfamily. Expressed in prolactin-secreting adenomas. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of human Ortholog: 2q24.2
Cellular Component:  plasma membrane
Biological Process:  regulation of ion transmembrane transport
Reference #:  Q9NS40 (UniProtKB)
Alt. Names/Synonyms: eag related protein 3; Eag-related protein 3; ERG-3; ERG3; ether-a-go-go related gene potassium channel 3; Ether-a-go-go-related gene potassium channel 3; Ether-a-go-go-related protein 3; hERG-3; HERG3; KCNH7; Kv11.3; MGC45986; potassium channel subunit HERG-3; potassium channel, voltage gated eag related subfamily H, member 7; Potassium voltage-gated channel subfamily H member 7; potassium voltage-gated channel, subfamily H (eag-related), member 7; Voltage-gated potassium channel subunit Kv11.3
Gene Symbols: KCNH7
Molecular weight: 135,000 Da
Basal Isoelectric point: 7.57  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein