RANGAP1 GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export. Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export. Belongs to the RNA1 family. Highly expressed in brain, thymus and testis. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Ras
Cellular Component: 
Reference #:  F1MFD5 (UniProtKB)
Alt. Names/Synonyms: Ran GTPase activating protein 1; RANGAP1
Gene Symbols: RANGAP1
Molecular weight: 62,942 Da
Basal Isoelectric point: 4.63  Predict pI for various phosphorylation states
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RANGAP1
Protein Structure Not Found.


Cross-references to other databases:  Pfam  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene