CHODL May play a role in the development of the nervous system such as in neurite outgrowth and elongation. May be involved in motor axon growth and guidance. Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. B lymphocytes express isoform 2 only; peripheral blood T lymphocytes express isoform 3 only; granulocytes and monocytes express neither isoform 2 nor isoform 3. During development of T lymphocytes, bone marrow progenitor cells express isoform 2 only; thymocytes at different stages of maturation express predominantly isoform 2 and weakly isoform 3, and mature thymocytes express only isoform 2. 4 human isoforms generated by alternative promoter usage or alternative splicing have been reported. Note: This description may include information from UniProtKB.
Protein type: Endoplasmic reticulum; Membrane protein, integral
Chromosomal Location of Human Ortholog: 21q21.1
Cellular Component:  cytoplasm; endoplasmic reticulum membrane; integral component of membrane; perinuclear region of cytoplasm
Molecular Function:  carbohydrate binding
Biological Process:  muscle organ development
Reference #:  Q9H9P2 (UniProtKB)
Alt. Names/Synonyms: C21orf68; CHODL; Chondrolectin; FLJ12627; MT75; PRED12; Transmembrane protein MT75
Gene Symbols: CHODL
Molecular weight: 30,431 Da
Basal Isoelectric point: 6.38  Predict pI for various phosphorylation states
Select Structure to View Below

CHODL

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein