DAZAP2
Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Down-regulated in multiple myeloma. 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Unknown function |
Chromosomal Location of human Ortholog: 12q13.13 |
Cellular Component:
cytoplasm; cytoplasmic stress granule; nuclear body; nuclear speck; nucleus; protein-containing complex
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Molecular Function:
DNA-binding transcription factor binding; identical protein binding; mitogen-activated protein kinase kinase kinase binding; p53 binding; protein binding; protein serine/threonine kinase activator activity; protein serine/threonine kinase binding; receptor tyrosine kinase binding; ubiquitin protein ligase binding; WW domain binding
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Biological Process:
positive regulation of protein serine/threonine kinase activity; positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding; protein destabilization; stress granule assembly
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Reference #:
Q15038
(UniProtKB)
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Alt. Names/Synonyms: DAZ associated protein 2; DAZ-associated protein 2; DAZAP2; DAZP2; deleted in azoospermia associated protein 2; Deleted in azoospermia-associated protein 2; KIAA0058; MGC14319; MGC766; proline-rich transcript in brain; proline-rich transcript, brain-expressed protein; PRTB
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Gene Symbols: DAZAP2
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Molecular weight:
17,319 Da
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Basal Isoelectric point:
6.69
Predict pI for various phosphorylation states
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