ATRN Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 2 F1|2 63.26 cM
Cellular Component:  cytoplasm; extracellular space; integral component of membrane; membrane; plasma membrane
Molecular Function:  carbohydrate binding; protein binding; signaling receptor activity
Biological Process:  animal organ morphogenesis; cerebellum development; inflammatory response; myelination; pigmentation; regulation of multicellular organism growth; response to oxidative stress; tissue development
Reference #:  Q9WU60 (UniProtKB)
Alt. Names/Synonyms: Atrn; Attractin; AW558010; mahogany; Mg; Mgca; mKIAA0548; OTTMUSP00000016559; Protein mahogany
Gene Symbols: Atrn
Molecular weight: 158,058 Da
Basal Isoelectric point: 7.14  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene