LASS2
Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis. Expressed in kidney, liver, brain, heart, placenta and lung. Note: This description may include information from UniProtKB.
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Protein type: DNA-binding; Membrane protein, integral; Membrane protein, multi-pass; Transferase |
Chromosomal Location of human Ortholog: 1q21.3 |
Cellular Component:
endoplasmic reticulum; endoplasmic reticulum membrane
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Molecular Function:
DNA binding; protein binding; sphingosine N-acyltransferase activity
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Biological Process:
ceramide biosynthetic process; negative regulation of axon regeneration; negative regulation of Schwann cell migration; negative regulation of Schwann cell proliferation involved in axon regeneration; regulation of lipid metabolic process; sphingolipid biosynthetic process
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Reference #:
Q96G23
(UniProtKB)
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Alt. Names/Synonyms: Ceramide synthase 2; CerS2; FLJ10243; L3; LAG1 homolog, ceramide synthase 2; LAG1 longevity assurance 2; LAG1 longevity assurance homolog 2; LASS2; longevity assurance (LAG1, S. cerevisiae) homolog 2; MGC987; SP260; Sphingosine N-acyltransferase CERS2; TMSG1; Tumor metastasis-suppressor gene 1 protein
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Gene Symbols: CERS2
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Molecular weight:
44,876 Da
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Basal Isoelectric point:
9.03
Predict pI for various phosphorylation states
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