FAH Belongs to the FAH family. Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - tyrosine; EC; Hydrolase
Chromosomal Location of mouse Ortholog: 7 D3|7 48.36 cM
Cellular Component: 
Molecular Function:  catalytic activity; fumarylacetoacetase activity; hydrolase activity; metal ion binding
Biological Process:  arginine catabolic process; aromatic amino acid family metabolic process; homogentisate catabolic process; L-phenylalanine catabolic process; tyrosine catabolic process
Reference #:  P35505 (UniProtKB)
Alt. Names/Synonyms: Beta-diketonase; FAA; FAAA; Fah; Fumarylacetoacetase; Fumarylacetoacetate hydrolase; OTTMUSP00000030308; swst
Gene Symbols: Fah
Molecular weight: 46,176 Da
Basal Isoelectric point: 6.7  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene