ASAM
May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development. Predominantly expressed in epithelial cells within different tissues and in the white adipose tissue. Expressed at high levels in small intestine and placenta, at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney and lung and at low levels in the liver and peripheral blood leukocytes. Highly abundant in the intestine during embryo and fetal development (at protein level). Note: This description may include information from UniProtKB.
|
Protein type: Cell adhesion; Membrane protein, integral |
Chromosomal Location of human Ortholog: 11q24.1 |
Cellular Component:
bicellular tight junction; cytoplasmic microtubule; plasma membrane
|
Molecular Function:
protein binding
|
Biological Process:
digestive tract development
|
Disease: Congenital Short Bowel Syndrome
|
Reference #:
Q9H6B4
(UniProtKB)
|
Alt. Names/Synonyms: ACAM; Adipocyte adhesion molecule; adipocyte-specific adhesion molecule; AP000926.1; ASAM; CAR-like membrane protein; CLMP; Coxsackie- and adenovirus receptor-like membrane protein; CSBM; CSBS; CXADR like membrane protein; CXADR-like membrane protein; FLJ22415
|
Gene Symbols: CLMP
|
Molecular weight:
41,281 Da
|
Basal Isoelectric point:
8.11
Predict pI for various phosphorylation states
|