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FAT3
May play a role in the interactions between neurites derived from specific subsets of neurons during development. Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Membrane protein, integral |
| Chromosomal Location of human Ortholog: 11q14.3 |
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Cellular Component:
dendrite; plasma membrane
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Molecular Function:
calcium ion binding
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Biological Process:
cell morphogenesis involved in differentiation; cell-cell adhesion; dendrite development; homophilic cell adhesion via plasma membrane adhesion molecules; interneuron migration; negative regulation of dendrite development; retina layer formation
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Reference #:
Q8TDW7
(UniProtKB)
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Alt. Names/Synonyms: Cadherin family member 15; cadherin-related family member 10; CDHF15; CDHR10; FAT atypical cadherin 3; FAT tumor suppressor homolog 3; FAT tumor suppressor homolog 3 (Drosophila); FAT3; hFat3; KIAA1989; Protocadherin Fat 3
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Gene Symbols: FAT3
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Molecular weight:
501,978 Da
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Basal Isoelectric point:
4.72
Predict pI for various phosphorylation states
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