LHX8
Transcription factor involved in differentiation of certain neurons and mesenchymal cells. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
Protein type: Cell development/differentiation; DNA-binding; Transcription factor |
Chromosomal Location of human Ortholog: 1p31.1 |
Cellular Component:
chromatin; female germ cell nucleus; nucleus
|
Molecular Function:
DNA-binding transcription factor activity, RNA polymerase II-specific; metal ion binding; protein binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; sequence-specific double-stranded DNA binding
|
Biological Process:
female gonad development; forebrain neuron development; learning or memory; neuron differentiation; odontogenesis of dentin-containing tooth; regulation of transcription by RNA polymerase II
|
Reference #:
Q68G74
(UniProtKB)
|
Alt. Names/Synonyms: Lhx7; LHX8; LIM homeobox 8; LIM homeobox protein 8; LIM-homeodomain protein Lhx8; LIM/homeobox protein Lhx8
|
Gene Symbols: LHX8
|
Molecular weight:
39,301 Da
|
Basal Isoelectric point:
8.61
Predict pI for various phosphorylation states
|