S6
May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. Belongs to the eukaryotic ribosomal protein eS6 family. Note: This description may include information from UniProtKB.
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Protein type: Translation |
Chromosomal Location of mouse Ortholog: 4|4 C4 |
Cellular Component:
cell body; cytoplasm; cytoplasmic ribonucleoprotein granule; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; dendrite; endoplasmic reticulum; GABA-ergic synapse; nucleolus; nucleus; perinuclear region of cytoplasm; polysome; presynapse; ribonucleoprotein complex; ribosome; small ribosomal subunit; small-subunit processome
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Molecular Function:
mRNA binding; protein binding; protein kinase binding; structural constituent of ribosome
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Biological Process:
activation-induced cell death of T cells; cellular response to ethanol; cytoplasmic translation; erythrocyte development; G1/S transition of mitotic cell cycle; gastrulation; glucose homeostasis; mammalian oogenesis stage; mitotic cell cycle; mitotic cell cycle checkpoint signaling; negative regulation of apoptotic process; negative regulation of bicellular tight junction assembly; placenta development; positive regulation of apoptotic process; positive regulation of cell population proliferation; response to insulin; ribosomal small subunit assembly; ribosomal small subunit biogenesis; rRNA processing; T cell differentiation in thymus; T cell proliferation involved in immune response; TOR signaling
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Reference #:
P62754
(UniProtKB)
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Alt. Names/Synonyms: 40S ribosomal protein S6; MGC102571; MGC103209; OTTMUSP00000008183; Phosphoprotein NP33; ribosomal protein S6; Rps6; RS6; S6; S6R; Small ribosomal subunit protein eS6
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Gene Symbols: Rps6
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Molecular weight:
28,681 Da
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Basal Isoelectric point:
10.85
Predict pI for various phosphorylation states
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CST Pathways:
Growth And Differentiation Control by MAPKs
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PI3K/Akt Signaling
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Translation: eIF4E and p70S6K
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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