|
ZCD1
Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. Expression is reduced in cells derived from cystic fibrosis patients. Note: This description may include information from UniProtKB.
|
| Protein type: Membrane protein, integral; Mitochondrial |
| Chromosomal Location of human Ortholog: 10q21.1 |
|
Cellular Component:
mitochondrial outer membrane; mitochondrion
|
|
Molecular Function:
2 iron, 2 sulfur cluster binding; identical protein binding; L-cysteine transaminase activity; metal ion binding; protein homodimerization activity; pyridoxal phosphate binding
|
|
Biological Process:
protein maturation by [2Fe-2S] cluster transfer; regulation of autophagy; regulation of cellular respiration
|
|
Reference #:
Q9NZ45
(UniProtKB)
|
|
Alt. Names/Synonyms: C10orf70; CDGSH iron sulfur domain 1; CDGSH iron sulfur domain-containing protein 1; CDGSH iron-sulfur domain-containing protein 1; CISD1; MDS029; MGC14684; MitoNEET; ZCD1; zinc finger CDGSH-type domain 1; zinc finger, CDGSH-type domain 1
|
|
Gene Symbols: CISD1
|
|
Molecular weight:
12,199 Da
|
|
Basal Isoelectric point:
9.2
Predict pI for various phosphorylation states
|
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
|
