CPPED1 Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes. Belongs to the metallophosphoesterase superfamily. CPPED1 family. Expressed in subcutaneous adipose tissue. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Hydrolase
Chromosomal Location of human Ortholog: 16p13.12
Cellular Component:  azurophil granule lumen; cytosol; extracellular region; plasma membrane
Molecular Function:  metal ion binding; myosin phosphatase activity
Reference #:  Q9BRF8 (UniProtKB)
Alt. Names/Synonyms: calcineurin like phosphoesterase domain containing 1; calcineurin-like phosphoesterase domain containing 1; Calcineurin-like phosphoesterase domain-containing protein 1; complete S transactivated protein 1; Complete S-transactivated protein 1; CPPED; CPPED1; CSTP1; FLJ11151; Serine/threonine-protein phosphatase CPPED1
Gene Symbols: CPPED1
Molecular weight: 35,548 Da
Basal Isoelectric point: 5.79  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein