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eIF2B-epsilon
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Belongs to the eIF-2B gamma/epsilon subunits family. Note: This description may include information from UniProtKB.
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| Protein type: Translation; Translation initiation |
| Chromosomal Location of rat Ortholog: 11q23 |
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Cellular Component:
cytoplasm; cytosol; eukaryotic translation initiation factor 2B complex; nucleus
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Molecular Function:
guanyl-nucleotide exchange factor activity; protein binding; translation initiation factor activity; translation initiation factor binding
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Biological Process:
astrocyte development; astrocyte differentiation; hippocampus development; myelination; oligodendrocyte development; ovarian follicle development; positive regulation of apoptotic process; positive regulation of translation; positive regulation of translational initiation; response to endoplasmic reticulum stress; response to glucose; response to heat; response to peptide hormone; T cell receptor signaling pathway; translational initiation
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Reference #:
Q64350
(UniProtKB)
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Alt. Names/Synonyms: EI2BE; eIF-2B GDP-GTP exchange factor subunit epsilon; eIF2B-epsilon; Eif2b5; Eif2be; eukaryotic translation initiation factor 2B, subunit 5 epsilon; initiation factor eIF-2Be; Translation initiation factor eIF-2B subunit epsilon
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Gene Symbols: Eif2b5
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Molecular weight:
80,206 Da
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Basal Isoelectric point:
4.9
Predict pI for various phosphorylation states
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CST Pathways:
Translation: eIF2
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Translational Control
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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