TRHR Receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Note: This description may include information from UniProtKB.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 15 B3.2|15 16.82 cM
Cellular Component:  cell surface; integral component of membrane; membrane; plasma membrane
Molecular Function:  G protein-coupled receptor activity; protein homodimerization activity; thyrotropin-releasing hormone receptor activity
Biological Process:  G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration; positive regulation of protein homodimerization activity; signal transduction
Reference #:  P21761 (UniProtKB)
Alt. Names/Synonyms: MGC124380; MGC124381; Thyroliberin receptor; thyrotropin releasing hormone receptor; Thyrotropin-releasing hormone receptor; TRFR; TRH-R; Trhr
Gene Symbols: Trhr
Molecular weight: 44,559 Da
Basal Isoelectric point: 8.7  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene