amphiphysin
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. Neurons, certain endocrine cell types and spermatocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Vesicle |
Chromosomal Location of rat Ortholog: 17q11 |
Cellular Component:
axon terminus; cytoplasm; cytoskeleton; extrinsic component of synaptic vesicle membrane; glutamatergic synapse; intracellular membrane-bounded organelle; leading edge membrane; photoreceptor ribbon synapse; plasma membrane; presynapse; presynaptic endocytic zone; synapse; synaptic vesicle
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Molecular Function:
phosphatase binding; phospholipid binding; protein binding; protein-containing complex binding
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Biological Process:
learning; positive regulation of endocytosis; positive regulation of GTPase activity; synaptic vesicle endocytosis
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Reference #:
O08838
(UniProtKB)
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Alt. Names/Synonyms: Amph; Amph1; Amphiphysin; amphiphysin 1
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Gene Symbols: Amph
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Molecular weight:
74,878 Da
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Basal Isoelectric point:
4.57
Predict pI for various phosphorylation states
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