Protein type: GAP; GAP, Ras; Motility/polarity/chemotaxis
Chromosomal Location of human Ortholog: 1q22
Cellular Component:  cell cortex; cell-cell junction; cytosol; lateral plasma membrane
Molecular Function:  actin filament binding; calmodulin binding; GTPase activator activity; myosin VI light chain binding; protein binding; small GTPase binding
Biological Process:  cellular response to organic substance; ERK1 and ERK2 cascade; G1/S transition of mitotic cell cycle; gene expression; mammary gland epithelial cell proliferation; mitotic actomyosin contractile ring assembly actin filament organization; negative regulation of gene expression; positive regulation of gene expression; positive regulation of mammary gland epithelial cell proliferation; positive regulation of MAPK cascade; positive regulation of protein phosphorylation; protein phosphorylation; Ras protein signal transduction; regulation of cell size; regulation of GTPase activity
Reference #:  Q86VI3 (UniProtKB)
Alt. Names/Synonyms: IQ motif containing GTPase activating protein 3; IQGA3; IQGAP3; MGC10170; MGC10831; MGC1947; Ras GTPase-activating-like protein IQGAP3
Gene Symbols: IQGAP3
Molecular weight: 184,699 Da
Basal Isoelectric point: 7.34  Predict pI for various phosphorylation states
CST Pathways:  Adherens Junction Dynamics
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein