DRAK2 Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. Note: This description may include information from UniProtKB.
Protein type: CAMK group; DAPK family; EC 2.7.11.1; Kinase, protein; Protein kinase, CAMK; Protein kinase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 9q31
Cellular Component:  actin cytoskeleton; endoplasmic reticulum-Golgi intermediate compartment; nucleus; plasma membrane
Molecular Function:  ATP binding; protein binding; protein kinase activity; protein serine/threonine kinase activity
Biological Process:  apoptotic process; intracellular signal transduction; positive regulation of fibroblast apoptotic process; programmed cell death; protein autophosphorylation; protein phosphorylation
Reference #:  Q91XS8 (UniProtKB)
Alt. Names/Synonyms: DAP kinase-related apoptosis-inducing protein kinase 2; death-associated protein kinase-related 2; Drak2; serine/threonine kinase 17b; serine/threonine kinase 17b (apoptosis-inducing); Serine/threonine-protein kinase 17B; ST17B; Stk17b
Gene Symbols: Stk17b
Molecular weight: 42,133 Da
Basal Isoelectric point: 5.02  Predict pI for various phosphorylation states
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DRAK2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene