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TAF6L
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Belongs to the TAF6 family. Note: This description may include information from UniProtKB.
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| Protein type: Transcription initiation complex |
| Chromosomal Location of human Ortholog: 11q12.3 |
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Cellular Component:
histone deacetylase complex; nucleoplasm; nucleus; SAGA complex; SLIK (SAGA-like) complex; transcription factor TFIID complex
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Molecular Function:
DNA binding; protein binding; protein heterodimerization activity; RNA polymerase II general transcription initiation factor activity; transcription coactivator activity
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Biological Process:
chromatin remodeling; histone acetylation; histone H3 acetylation; monoubiquitinated histone deubiquitination; monoubiquitinated histone H2A deubiquitination; positive regulation of DNA-templated transcription; regulation of DNA repair; regulation of DNA-templated transcription; regulation of RNA splicing; regulation of somatic stem cell population maintenance; regulation of transcription by RNA polymerase II; RNA polymerase II preinitiation complex assembly
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Reference #:
Q9Y6J9
(UniProtKB)
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Alt. Names/Synonyms: FLJ11136; MGC4288; p300/CBP-associated factor (PCAF)-associated factor 65; PAF65-alpha; PAF65A; PCAF-associated factor 65 alpha; PCAF-associated factor 65-alpha; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; TAF6L; TATA-box binding protein associated factor 6 like
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Gene Symbols: TAF6L
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Molecular weight:
67,814 Da
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Basal Isoelectric point:
9.14
Predict pI for various phosphorylation states
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