NDUFB11 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFB11 subunit family. Ubiquitous. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; EC; Membrane protein, integral; Mitochondrial; Oxidoreductase
Chromosomal Location of Human Ortholog: Xp11.3
Cellular Component:  integral component of membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex I; mitochondrion
Molecular Function:  protein binding
Biological Process:  mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly
Disease: Linear Skin Defects With Multiple Congenital Anomalies 3; Microphthalmia, Syndromic 7; Mitochondrial Complex I Deficiency, Nuclear Type 30
Reference #:  Q9NX14 (UniProtKB)
Alt. Names/Synonyms: CI-ESSS; complex I NP17.3 subunit; Complex I-ESSS; ESSS; FLJ20494; MC1DN30; MGC111182; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial; NADH-ubiquinone oxidoreductase ESSS subunit; NADH:ubiquinone oxidoreductase subunit B11; NDUBB; NDUFB11; Neuronal protein 17.3; Np15; Np17.3; p17.3
Gene Symbols: NDUFB11
Molecular weight: 17,317 Da
Basal Isoelectric point: 5.17  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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