TBC1D14 Negative regulator of starvation-induced autophagosome formation. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: GAP; GAP, Rab
Chromosomal Location of human Ortholog: 4p16.1
Cellular Component:  autophagosome; cytosol; Golgi apparatus; intracellular membrane-bounded organelle; nucleoplasm; recycling endosome
Molecular Function:  GTPase activator activity; protein binding; protein kinase binding
Biological Process:  activation of GTPase activity; autophagy; negative regulation of autophagy; recycling endosome to Golgi transport; regulation of autophagosome assembly; regulation of cilium assembly
Reference #:  Q9P2M4 (UniProtKB)
Alt. Names/Synonyms: FLJ32400; KIAA1322; TBC1 domain family member 14; TBC1 domain family, member 14; TBC14; TBC1D14
Gene Symbols: TBC1D14
Molecular weight: 78,137 Da
Basal Isoelectric point: 6.57  Predict pI for various phosphorylation states
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TBC1D14

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein