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ACO2
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Belongs to the aconitase/IPM isomerase family. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - citrate (TCA) cycle; Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 4.2.1.3; Lyase; Mitochondrial |
| Chromosomal Location of rat Ortholog: 7q34 |
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Cellular Component:
cytosol; mitochondrion
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Molecular Function:
3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; aconitate hydratase activity; citrate dehydratase activity; iron ion binding; metal ion binding; protein binding
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Biological Process:
citrate metabolic process; isocitrate metabolic process; liver development; response to isolation stress; tricarboxylic acid cycle
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Reference #:
Q9ER34
(UniProtKB)
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Alt. Names/Synonyms: Aco2; ACON; Aconitase; aconitase 2, mitochondrial; Aconitate hydratase, mitochondrial; Citrate hydro-lyase; mitochondrial aconitase (nuclear aco2 gene)
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Gene Symbols: Aco2
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Molecular weight:
85,433 Da
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Basal Isoelectric point:
7.87
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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