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BOLL
Probable RNA-binding protein, which may be required during spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation. Belongs to the RRM DAZ family. Testis specific. Not expressed in early embryos, primordial germ cells and spermatogonial cells. First expressed in the cytoplasm of spermatocytes and then persists through meiosis. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Translation |
| Chromosomal Location of human Ortholog: 2q33.1 |
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Cellular Component:
cytoplasm
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Molecular Function:
identical protein binding; mRNA 3'-UTR binding; protein binding; translation activator activity
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Biological Process:
3'-UTR-mediated mRNA stabilization; cell differentiation; meiotic cell cycle; positive regulation of translational initiation; spermatogenesis
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Reference #:
Q8N9W6
(UniProtKB)
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Alt. Names/Synonyms: bol, boule-like; bol, boule-like (Drosophila); BOLL; BOULE; boule homolog, RNA binding protein; boule-like RNA binding protein; Protein boule-like
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Gene Symbols: BOLL
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Molecular weight:
31,301 Da
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Basal Isoelectric point:
6.59
Predict pI for various phosphorylation states
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