TTC19 Required for the preservation of the structural and functional integrity of mitochondrial respiratory complex III by allowing the physiological turnover of the Rieske protein UQCRFS1. Involved in the clearance of UQCRFS1 N-terminal fragments, which are produced upon incorporation of UQCRFS1 into the complex III and whose presence is detrimental for its catalytic activity. Belongs to the TTC19 family. Note: This description may include information from UniProtKB.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 11|11 B2
Cellular Component:  membrane; mitochondrial inner membrane; mitochondrion; respiratory chain
Molecular Function:  protein binding
Biological Process:  mitochondrial respiratory chain complex III assembly; oxidation-reduction process
Reference #:  Q8CC21 (UniProtKB)
Alt. Names/Synonyms: 2010204O13Rik; 2810460C24Rik; AI505442; OTTMUSP00000006049; tetratricopeptide repeat domain 19; Tetratricopeptide repeat protein 19; Tetratricopeptide repeat protein 19, mitochondrial; TPR repeat protein 19; Ttc19
Gene Symbols: Ttc19
Molecular weight: 41,234 Da
Basal Isoelectric point: 5.87  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene