TMEM123 Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability. Belongs to the CD164 family. Ubiquitous. Not expressed in ovary. Expressed in keratinocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q22.2
Cellular Component:  external side of plasma membrane; integral component of membrane
Molecular Function:  protein binding; signaling receptor activity
Biological Process:  oncosis
Reference #:  Q8N131 (UniProtKB)
Alt. Names/Synonyms: KCT-3; KCT3; keratinocytes associated transmembrane protein 3; Keratinocytes-associated transmembrane protein 3; PORIM; Porimin; PORMIN; pro oncosis receptor inducing membrane injury; Pro-oncosis receptor inducing membrane injury; serine/threonine-rich receptor; TMEM123; Transmembrane protein 123
Gene Symbols: TMEM123
Molecular weight: 21,531 Da
Basal Isoelectric point: 8.76  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene