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NIBAN1
Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response. Belongs to the Niban family. Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of human Ortholog: 1q25.3 |
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Cellular Component:
cytoplasm; cytosol; plasma membrane
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Molecular Function:
protein binding
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Biological Process:
negative regulation of protein phosphorylation; positive regulation of protein phosphorylation; positive regulation of translation; response to endoplasmic reticulum stress
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Reference #:
Q9BZQ8
(UniProtKB)
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Alt. Names/Synonyms: C1orf24; cell growth inhibiting protein 39; Cell growth-inhibiting gene 39 protein; FAM129A; family with sequence similarity 129 member A; family with sequence similarity 129, member A; FLJ38228; GIG39; NIBA1; NIBAN; niban apoptosis regulator 1; NIBAN1; Protein FAM129A; Protein Niban; Protein Niban 1
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Gene Symbols: NIBAN1
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Molecular weight:
103,135 Da
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Basal Isoelectric point:
4.74
Predict pI for various phosphorylation states
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