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CK2B
Participates in Wnt signaling. Plays a complex role in regulating the basal catalytic activity of the alpha subunit. Belongs to the casein kinase 2 subunit beta family. Note: This description may include information from UniProtKB.
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| Protein type: Protein kinase, regulatory subunit |
| Chromosomal Location of mouse Ortholog: 17 B1|17 18.59 cM |
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Cellular Component:
cell projection; chromatin; cytoplasm; cytosol; nuclear matrix; nucleus; PcG protein complex; plasma membrane; PML body; protein kinase CK2 complex
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Molecular Function:
chromatin binding; identical protein binding; metal ion binding; protein binding; protein domain specific binding; protein kinase regulator activity; protein serine/threonine kinase activity; protein-macromolecule adaptor activity; ribonucleoprotein complex binding; RNA polymerase II-specific DNA-binding transcription factor binding; signaling receptor binding
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Biological Process:
adiponectin-activated signaling pathway; endothelial tube morphogenesis; negative regulation of blood vessel endothelial cell migration; negative regulation of viral life cycle; peptidyl-threonine phosphorylation; positive regulation of activin receptor signaling pathway; positive regulation of pathway-restricted SMAD protein phosphorylation; protein phosphorylation; Wnt signaling pathway
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Reference #:
P67871
(UniProtKB)
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Alt. Names/Synonyms: casein kinase 2, beta polypeptide; Casein kinase II subunit beta; casein kinase II, beta subunit; CK II beta; CK2B; Ck2n; CSK2B; Csnk2b; Phosvitin
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Gene Symbols: Csnk2b
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Molecular weight:
24,942 Da
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Basal Isoelectric point:
5.33
Predict pI for various phosphorylation states
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CST Pathways:
Adherens Junction Dynamics
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NF-kB Signaling
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