BNIP2 Implicated in the suppression of cell death. Interacts with the BCL-2 and adenovirus E1B 19 kDa proteins. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Apoptosis; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 15q22.2
Cellular Component:  cytoplasm; cytosol; intracellular membrane-bounded organelle; nuclear envelope; perinuclear region of cytoplasm
Molecular Function:  calcium ion binding; GTPase activator activity; protein binding
Biological Process:  apoptotic process; negative regulation of apoptotic process; positive regulation of GTPase activity; positive regulation of muscle cell differentiation
Reference #:  Q12982 (UniProtKB)
Alt. Names/Synonyms: BCL2 interacting protein 2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BCL2/adenovirus E1B 19kDa interacting protein 2; BNIP-2; BNIP2; NIP2
Gene Symbols: BNIP2
Molecular weight: 36,018 Da
Basal Isoelectric point: 4.7  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein