TBPL2 Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process. Belongs to the TBP family. Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 14q22.3
Cellular Component:  cytoplasm; nucleus
Molecular Function:  DNA-binding transcription factor activity, RNA polymerase II-specific
Biological Process:  multicellular organism development; negative regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II
Reference #:  Q6SJ96 (UniProtKB)
Alt. Names/Synonyms: TATA box-binding protein-like 2; TATA box-binding protein-like protein 2; TATA box-binding protein-related factor 3; TATA-box binding protein like 2; TBP-like 2; TBP-like protein 2; TBP-related factor 3; TBP2; TBPL2; TRF3
Gene Symbols: TBPL2
Molecular weight: 41,524 Da
Basal Isoelectric point: 6.05  Predict pI for various phosphorylation states
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Protein Structure Not Found.

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