CCL27 Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10. Belongs to the intercrine beta (chemokine CC) family. Testis, thymus, placenta, ovary and skin. Note: This description may include information from UniProtKB.
Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9p13.3
Cellular Component:  extracellular region; extracellular space
Molecular Function:  CCR3 chemokine receptor binding; chemokine activity; protein binding
Biological Process:  cell chemotaxis; cell-cell signaling; chemotaxis; G protein-coupled receptor signaling pathway; immune response; regulation of signaling receptor activity
Reference #:  Q9Y4X3 (UniProtKB)
Alt. Names/Synonyms: ALP; C-C motif chemokine 27; C-C motif chemokine ligand 27; CC chemokine ILC; CCL27; chemokine (C-C motif) ligand 27; CTACK; CTAK; cutaneous T-cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESkine; IL-11 R-alpha-locus chemokine; IL-11 Ralpha-locus chemokine; ILC; PESKY; SCYA27; Skinkine; small inducible cytokine subfamily A (Cys-Cys), member 27; Small-inducible cytokine A27
Gene Symbols: CCL27
Molecular weight: 12,618 Da
Basal Isoelectric point: 8.95  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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