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UQCRC1
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily. Note: This description may include information from UniProtKB.
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| Protein type: EC 1.10.2.2; Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase |
| Chromosomal Location of human Ortholog: 3p21.31 |
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Cellular Component:
mitochondrial inner membrane; mitochondrial respirasome; mitochondrial respiratory chain complex III; mitochondrion
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Molecular Function:
metal ion binding; protein binding; protein-containing complex binding; ubiquinol-cytochrome-c reductase activity; ubiquitin protein ligase binding
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Biological Process:
aerobic respiration; cellular respiration; mitochondrial electron transport, ubiquinol to cytochrome c; oxidative phosphorylation; proton transmembrane transport; response to activity; response to alkaloid
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Disease: Parkinsonism With Polyneuropathy
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Reference #:
P31930
(UniProtKB)
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Alt. Names/Synonyms: Complex III subunit 1; Core protein I; Cytochrome b-c1 complex subunit 1, mitochondrial; D3S3191; QCR1; ubiquinol-cytochrome c reductase core protein 1; ubiquinol-cytochrome c reductase core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1; UQCR1; UQCRC1
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Gene Symbols: UQCRC1
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Molecular weight:
52,646 Da
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Basal Isoelectric point:
5.94
Predict pI for various phosphorylation states
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