UQCRC1 This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily. Note: This description may include information from UniProtKB.
Protein type: EC 1.10.2.2; Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase
Chromosomal Location of human Ortholog: 3p21.31
Cellular Component:  mitochondrial inner membrane; mitochondrial respirasome; mitochondrial respiratory chain complex III; mitochondrion
Molecular Function:  metal ion binding; protein binding; protein-containing complex binding; ubiquinol-cytochrome-c reductase activity; ubiquitin protein ligase binding
Biological Process:  aerobic respiration; cellular respiration; mitochondrial electron transport, ubiquinol to cytochrome c; oxidative phosphorylation; proton transmembrane transport; response to activity; response to alkaloid
Disease: Parkinsonism With Polyneuropathy
Reference #:  P31930 (UniProtKB)
Alt. Names/Synonyms: Complex III subunit 1; Core protein I; Cytochrome b-c1 complex subunit 1, mitochondrial; D3S3191; QCR1; ubiquinol-cytochrome c reductase core protein 1; ubiquinol-cytochrome c reductase core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1; UQCR1; UQCRC1
Gene Symbols: UQCRC1
Molecular weight: 52,646 Da
Basal Isoelectric point: 5.94  Predict pI for various phosphorylation states
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UQCRC1

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene