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TULP4
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the TUB family. Expressed mainly in the brain, skeletal muscle, testis and kidney. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Ubiquitin conjugating system |
| Chromosomal Location of human Ortholog: 6q25.3 |
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Cellular Component:
cytoplasm; cytosol
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Molecular Function:
protein binding
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Biological Process:
protein ubiquitination
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Reference #:
Q9NRJ4
(UniProtKB)
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Alt. Names/Synonyms: KIAA1397; TUB like protein 4; tubby like protein 4; tubby super-family protein; Tubby superfamily protein; Tubby-like protein 4; Tubby-related protein 4; TUBL4; TULP4; TUSP
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Gene Symbols: TULP4
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Molecular weight:
169,000 Da
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Basal Isoelectric point:
7.49
Predict pI for various phosphorylation states
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