TULP4 May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the TUB family. Expressed mainly in the brain, skeletal muscle, testis and kidney. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Ubiquitin conjugating system
Chromosomal Location of human Ortholog: 6q25.3
Cellular Component:  cytoplasm; cytosol
Molecular Function:  protein binding
Biological Process:  protein ubiquitination
Reference #:  Q9NRJ4 (UniProtKB)
Alt. Names/Synonyms: KIAA1397; TUB like protein 4; tubby like protein 4; tubby super-family protein; Tubby superfamily protein; Tubby-like protein 4; Tubby-related protein 4; TUBL4; TULP4; TUSP
Gene Symbols: TULP4
Molecular weight: 169,000 Da
Basal Isoelectric point: 7.49  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein