TXNL4A
Plays role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). Belongs to the DIM1 family. Note: This description may include information from UniProtKB.
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Protein type: RNA-binding; Spliceosome |
Chromosomal Location of human Ortholog: 18q23 |
Cellular Component:
cytosol; nuclear membrane; nucleoplasm; nucleus; spliceosomal complex; U2-type precatalytic spliceosome; U4/U6 x U5 tri-snRNP complex; U5 snRNP
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Molecular Function:
protein binding
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Biological Process:
cell cycle; cell division; mRNA splicing, via spliceosome; RNA splicing, via transesterification reactions; spliceosomal complex assembly
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Disease: Burn-mckeown Syndrome
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Reference #:
P83876
(UniProtKB)
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Alt. Names/Synonyms: BMKS; DIB1; DIM1; DIM1 protein homolog; HsT161; SNRNP15; Spliceosomal U5 snRNP-specific 15 kDa protein; thioredoxin like 4A; thioredoxin-like 4; thioredoxin-like 4A; Thioredoxin-like protein 4A; Thioredoxin-like U5 snRNP protein U5-15kD; TXN4A; TXNL4; TXNL4A; U5-15kD
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Gene Symbols: TXNL4A
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Molecular weight:
16,786 Da
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Basal Isoelectric point:
5.53
Predict pI for various phosphorylation states
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