hnRNP A/B Binds single-stranded RNA. Has a high affinity for G-rich and U-rich regions of hnRNA. Also binds to APOB mRNA transcripts around the RNA editing site. Ubiquitous. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of Human Ortholog: 11|11 B1.3
Cellular Component:  cytoplasm; nucleoplasm; nucleus; presynaptic cytosol; ribonucleoprotein complex; RNA polymerase II transcription factor complex
Molecular Function:  DNA binding; nucleic acid binding; protein binding; RNA binding; sequence-specific DNA binding; sequence-specific double-stranded DNA binding
Biological Process:  epithelial to mesenchymal transition; negative regulation of transcription by RNA polymerase II; positive regulation of transcription, DNA-templated
Reference #:  Q99020 (UniProtKB)
Alt. Names/Synonyms: 3010025C11Rik; CArG-binding factor-A; CBF-A; Cgbfa; Heterogeneous nuclear ribonucleoprotein A/B; hnRNP A/B; Hnrnpab; Hnrpab; OTTMUSP00000005762; ROAA; S1 protein D2
Gene Symbols: Hnrnpab
Molecular weight: 30,831 Da
Basal Isoelectric point: 7.69  Predict pI for various phosphorylation states
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hnRNP A/B

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene