WIF1 Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation. Note: This description may include information from UniProtKB.
Protein type: Inhibitor; Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: 12q14.3
Cellular Component:  cell surface; extracellular region
Molecular Function:  protein binding; signaling receptor binding; Wnt-protein binding
Biological Process:  anatomical structure development; negative regulation of Wnt signaling pathway; positive regulation of fat cell differentiation; signal transduction; Wnt signaling pathway
Reference #:  Q9Y5W5 (UniProtKB)
Alt. Names/Synonyms: WIF-1; WIF1; Wnt inhibitory factor 1
Gene Symbols: WIF1
Molecular weight: 41,528 Da
Basal Isoelectric point: 7.84  Predict pI for various phosphorylation states
CST Pathways:  Wnt/ß-Catenin Signaling
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene