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ARPP-21
Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons. Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level). 6 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Inhibitor |
| Chromosomal Location of mouse Ortholog: 9 F3|9 62.46 cM |
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Cellular Component:
cytoplasm
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Molecular Function:
calmodulin binding; nucleic acid binding
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Biological Process:
cellular response to heat
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Reference #:
Q9DCB4
(UniProtKB)
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Alt. Names/Synonyms: 0710001E13Rik; AI853636; ARP; ARP21; ARPP-21; Arpp21; cAMP-regulated phosphoprotein 21; cyclic AMP-regulated phosphoprotein, 21; D9Bwg1012e; protein phosphatase 1, regulatory (inhibitory) subunit 1C; R3hdm; R3hdm3; Rcs; Regulator of calmodulin signaling; Tarpp; thymocyte ARPP; Thymocyte cAMP-regulated phosphoprotein
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Gene Symbols: Arpp21
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Molecular weight:
88,567 Da
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Basal Isoelectric point:
7
Predict pI for various phosphorylation states
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