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ANKRD3
Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Expressed in hair follicles and skin. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.7.11.1; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; RIPK family; TKL group |
| Chromosomal Location of mouse Ortholog: 16|16 C4 |
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Cellular Component:
cytoplasm; membrane
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Molecular Function:
ATP binding; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity
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Biological Process:
morphogenesis of an epithelium; phosphorylation; positive regulation of NF-kappaB transcription factor activity; protein phosphorylation
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Reference #:
Q9ERK0
(UniProtKB)
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Alt. Names/Synonyms: 2310069J12Rik; AI552420; Ank; ANKK2; Ankrd3; ankyrin repeat domain 3; Ankyrin repeat domain-containing protein 3; DIk; OTTMUSP00000021567; PKC-associated protein kinase; PKC-regulated protein kinase; Pkk; receptor-interacting serine-threonine kinase 4; Receptor-interacting serine/threonine-protein kinase 4; RIP4; Ripk4
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Gene Symbols: Ripk4
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Molecular weight:
86,613 Da
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Basal Isoelectric point:
6.53
Predict pI for various phosphorylation states
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